@article {10.3844/ajbbsp.2026.22.02.016, article_type = {journal}, title = {Mechanism of Mulberry's Effect on Intestinal Flora and Motility}, author = {Zhao, Huizhen and Xie, Shijing and Li, Yuwen and Jiao, Yan and Zhang, Yuanyuan}, volume = {22}, number = {2}, year = {2026}, month = {Jul}, pages = {16-1}, doi = {10.3844/ajbbsp.2026.22.02.016}, url = {https://thescipub.com/abstract/ajbbsp.2026.22.02.016}, abstract = {Studies have indicated that mulberry consumption promotes intestinal motility and alleviates constipation, but the specific mechanism remains unclear. This study adopted a constipation mouse model to empirically analyze the effects of mulberry on intestinal motility, gut microbiota composition, and neurotransmitter levels, aiming to elucidate its mechanism of action. Key findings are as follows: 1) Compared with the model group, the treatment with mulberry extract significantly increased the moisture content of feces (MD). Among them, the increase in the high-dose group compared to MD was 137.5% (p< 0.05). It also accelerated the small intestine transport speed by 3.4 times and shortened the latency period for the first occurrence of black feces by 73.7% (p}, journal = {American Journal of Biochemistry and Biotechnology}, publisher = {Science Publications} }