Research Article Open Access

Optimization of α-Glucosidase Inhibitors Recovery from Rainbow Trout Hydrolysate Using GA-BP Neural Network

Yingke Chu1, Yanling Dong2, Qingfeng Rong2, Kun Yang2 and Lanlan Zhu1
  • 1 College of Agricultural Engineering and Food Science, Shandong University of Technology, Zibo, 255100, Shandong Province, China
  • 2 Test Center, Zichuan District Inspection and Test Center, Zibo, 255100, Shandong Province, China

Abstract

To enhance the value of by-products from rainbow trout processing, the inhibition rate of α-glucosidase (AGIR) is used as indicators. Optimization of rainbow trout hydrolysate extraction by comparing Response Surface Methodology (RSM) and BP Neural Network (BPNN) models. The RSM results: the AGIR is 55.02%. BPNN models predicted the optimal extraction conditions: 51℃ for temperature,1:2.3 for solid-liquid ratio, 4.15 h for time and 0.2334% for enzyme dosage. The reactions obtained under optimized conditions are as follows: the α-glucosidase inhibitory rate increased to 58.14%. This proves that the BPNN model can simultaneously improve the hydrolysis degree and α-glucosidase inhibition rate of the rainbow trout hydrolysate.

American Journal of Biochemistry and Biotechnology
Volume 21 No. 3, 2025, 401-411

DOI: https://doi.org/10.3844/ajbbsp.2025.401.411

Submitted On: 28 November 2024 Published On: 28 January 2026

How to Cite: Chu, Y., Dong, Y., Rong, Q., Yang, K. & Zhu, L. (2025). Optimization of α-Glucosidase Inhibitors Recovery from Rainbow Trout Hydrolysate Using GA-BP Neural Network. American Journal of Biochemistry and Biotechnology, 21(3), 401-411. https://doi.org/10.3844/ajbbsp.2025.401.411

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Keywords

  • Rainbow Trout
  • Enzymatic Hydrolysis Reaction
  • BP Neural Network